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The April 2018 protests in Nicaragua inaugurated the Latin American protest wave that subsequently spread across the region in 2019. The protests and their governmental suppression ushered Nicaraguan politics into a regime crisis. Yet, despite international pressure, the harsh reality of a serious economic downturn, low and diminishing public support and the continued opposition resistance throughout 2019, the orteguista regime has proven to be remarkably resilient to change. In fact, it has tightened its grip on power and managed to deflect demands for change during negotiations with the opposition which eventually failed. Focusing on the main opposition and regime actors and strategies, the article argues that the neopatrimonial characteristics of the regime explain this surprising resilience.